Appendices to Section 6.9
Neglected Diseases


Appendix 1 [pdf 960KB]  

Depoortere, E, Legros, D, Torreele, E. Developing a needs-based and rational approach to identify neglected diseases and select R&D projects that could maximally impact treatment options. Drugs for Neglected Diseases Working group, MSF, 2001: A thorough analysis of neglected diseases and the problems in priority setting. Includes analyses of different ways of presenting available data and proposes a “policy strategy” for priority setting for neglected diseases


Appendix 2 [pdf 102KB]  

Trouiller P, Olliaro P, Torreele E, Orbinski J, Laing R, Ford N. Drug development for neglected diseases: a deficient market and a public-health policy failure. Lancet. 2002 Jun 22;359(9324):2188-94. An in-depth analysis of the current pharmaceutical discovery process and the failure of the system to address the needs of neglected diseases.  
Reprinted with permission from Elsevier. (Lancet 2002;359(9324):2188-2194). The Lancet Homepage is at


Appendix 3 [pdf 463KB]  

Legros D, Ollivier G, Gastellu-Etchegorry M, Paquet C, Burri C, Jannin J, Buscher P. Treatment of human African trypanosomiasis--present situation and needs for research and development. Lancet Infect Dis. 2002 Jul;2(7):437-40. A needs-based analysis of the problems identified in treating HAT.
Reprinted with permission from Elsevier. (Lancet Infect Dis 2002;2(7):437-440).


Appendix 4 [pdf 2.2MB]  

Guerin PJ, Olliaro P, Sundar S, Boelaert M, Croft SL, Desjeux P, Wasunna MK, Bryceson AD. (2002a) Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda. Lancet Infect Dis. 2002 Aug;2(8):494-501. An analysis, carried out in a similar way to annex 4, of the needs-based priority agenda for a response to VL.  
Reprinted with permission from Elsevier. (Lancet Infect Dis 2002;2(8):494-501).


Appendix 5 [pdf 308KB]  

Ahoua L. & Torreele E. Prise en Charge de l’ulcère de Buruli: medicament disponibles et perspectives. Epicentre working paper, 2004. An analysis of the current treatment options for Buruli Ulcer including available treatments and future possibilities.


Appendix 6 [pdf 132KB]

ACP-EU Joint Parliamentary Assembly Resolution on poverty-related diseases and reproductive health in ACP States, ACP-EU 3640/04/fin. A clear commitment on the part of the EU to addressing health needs in developing countries, and affirms the EU responsibility to act.